The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern.
Saman AminiAnnika JacobsenOlga IvanovaPhilip LijnzaadJaap HeringaFrank C. P. HolstegeK. Anton FeenstraPatrick KemmerenPublished in: PLoS Comput. Biol. (2019)
Keyphrases
- gene expression
- transcription factors
- microarray
- binding sites
- protein interaction
- gene regulation
- gene expression data
- microarray data
- dna binding
- biological processes
- regulatory networks
- gene expression patterns
- biological knowledge
- differentially expressed
- regulatory elements
- gene selection
- component analysis
- genome wide
- biological networks
- differentially expressed genes
- computational biology
- transcription factor binding sites
- motif discovery
- genomic data
- cell cycle
- dna sequences
- high throughput
- saccharomyces cerevisiae
- co occurrence
- natural language processing
- data analysis