Pfam: multiple sequence alignments and HMM-profiles of protein domains.
Erik L. L. SonnhammerSean R. EddyEwan BirneyAlex BatemanRichard DurbinPublished in: Nucleic Acids Res. (1998)
Keyphrases
- multiple sequence alignments
- multiple sequence alignment
- protein sequences
- hidden markov models
- pairwise
- protein protein interactions
- protein structure prediction
- memory efficient
- secondary structure
- protein families
- phylogenetic trees
- sequence alignment
- multiple alignment
- biological sequences
- genetic algorithm
- computational biology
- sequence similarity
- amino acid sequences
- protein structure
- high precision
- similarity measure
- social networks