Transcription factor and microRNA co-regulatory loops: important regulatory motifs in biological processes and diseases.
Hong-Mei ZhangShuzhen KuangXushen XiongTianliuyun GaoChenglin LiuAn-Yuan GuoPublished in: Briefings Bioinform. (2015)
Keyphrases
- transcription factors
- binding sites
- biological processes
- gene expression
- dna sequences
- genome wide
- microarray
- gene regulation
- motif discovery
- dna binding
- sequence data
- regulatory networks
- computational biology
- cell cycle
- component analysis
- statistical significance
- transcription factor binding sites
- co occurrence
- high throughput
- gene sets
- systems biology
- signaling pathways
- highly correlated
- biomedical literature
- knowledge discovery
- statistical methods
- protein interaction
- high dimensionality