Accurate prediction of virus-host protein-protein interactions via a Siamese neural network using deep protein sequence embeddings.
Sumit MadanVictoria DeminaMarcus StapfOliver ErnstHolger FröhlichPublished in: Patterns (2022)
Keyphrases
- experimentally determined
- protein protein interactions
- protein sequences
- protein protein
- multiple sequence alignments
- protein function
- protein interaction
- high precision
- computational methods
- predicting protein
- protein secondary structure
- protein structure
- drug design
- biological processes
- high throughput
- computational approaches
- secondary structure
- gene ontology
- functional modules
- protein complexes
- systems biology
- protein structure prediction
- network topology
- biological networks
- network analysis
- biomedical literature
- wet lab
- protein interaction data
- protein interaction networks
- structural properties
- biological data
- protein secondary structure prediction
- genomic data
- interaction networks
- computational biology
- coarse grained
- network model
- social network analysis
- random walk
- high accuracy