Optimization of Therapeutic proteins to Delete T-Cell epitopes while Maintaining Beneficial Residue Interactions.
Andrew S. ParkerKarl E. GriswoldChris Bailey-KelloggPublished in: J. Bioinform. Comput. Biol. (2011)
Keyphrases
- living cells
- cellular processes
- amino acids
- protein structure prediction
- global optimization
- optimization problems
- protein functional
- optimization algorithm
- optimization method
- high throughput
- interaction networks
- contact map
- protein protein interactions
- optimization process
- immune response
- microscope images
- protein protein
- protein subcellular location
- protein function
- functional modules
- experimental conditions
- computational methods
- chemical compounds
- microscopy images
- molecular interactions
- signal transduction pathways