A conceptual and computational framework for modelling and understanding the non-equilibrium gene regulatory networks of mouse embryonic stem cells.
Richard B. GreavesSabine DietmannAustin SmithSusan StepneyJulianne D. HalleyPublished in: PLoS Comput. Biol. (2017)
Keyphrases
- computational framework
- gene regulatory networks
- biological processes
- computational model
- gene expression data
- reverse engineering
- gene regulatory
- network model
- gene networks
- biological data
- gene regulation
- regulatory networks
- boolean networks
- systems biology
- dynamic bayesian networks
- bayesian inference
- gene ontology
- databases
- microarray data
- microarray
- data management
- query language
- artificial intelligence
- neural network