A novel pathway mutation perturbation score predicts the clinical outcomes of immunotherapy.
Xiangmei LiYalan HeJiashuo WuJiayue QiuJi LiQian WangYing JiangJunwei HanPublished in: Briefings Bioinform. (2022)
Keyphrases
- health information systems
- genetic algorithm
- evolutionary algorithm
- differential evolution
- clinical data
- drug resistance
- clinical practice
- clinical information
- patient data
- fitness function
- clinically relevant
- medical domain
- information systems
- mutation operator
- clinical applications
- disease diagnosis
- medical data
- genetic algorithm ga
- population size
- electronic health records
- clinical guidelines
- crossover operator
- medical treatment
- perturbation method
- information retrieval