Chronic fatigue syndrome: identification of transcription factor (TFs) associated with gene expression for drug signature prediction.
Jyoti Kant ChoudhariMukesh Kumar VermaBiju Prava SahariahPublished in: Netw. Model. Anal. Health Informatics Bioinform. (2019)
Keyphrases
- transcription factors
- gene expression
- binding sites
- microarray
- transcriptional regulatory
- dna binding
- gene regulation
- gene expression data
- biological processes
- protein interaction
- component analysis
- genome wide
- regulatory networks
- microarray data
- gene expression levels
- saccharomyces cerevisiae
- computational biology
- dna sequences
- gene expression patterns
- drug design
- high throughput
- cell cycle
- biomedical literature
- motif discovery
- highly correlated
- transcription factor binding sites
- systems biology
- co occurrence
- transcriptional regulation
- microarray datasets
- high dimensionality
- gene sets
- gene expression profiles
- gene ontology
- biological networks