Exploration of the Parameter Space of an Ion Channel Kinetic Model by a Markov-Chain-Based Methodology.
Juan I. FeliceVerónica MilesiGabriel FabriciusPublished in: J. Chem. Inf. Model. (2024)
Keyphrases
- parameter space
- markov chain
- markov model
- transition probabilities
- markov process
- parameter values
- steady state
- transition matrix
- probabilistic model
- markov models
- monte carlo simulation
- experimental data
- stochastic process
- finite state
- objective function
- monte carlo
- statistical model
- mathematical model
- cross validation
- energy function
- parameter estimation
- likelihood function
- particle filter
- stationary distribution
- prior knowledge
- monte carlo method
- search algorithm