Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain.
Mary Pat BeaversMichael C. MyersParag P. ShahJeremy E. PurvisScott L. DiamondBarry S. CoopermanDonna M. HurynAmos B. Smith IIIPublished in: J. Chem. Inf. Model. (2008)
Keyphrases
- hiv protease
- binding sites
- protein protein interactions
- protein protein
- virtual screening
- coarse grained
- sequence analysis
- sequence data
- protein interaction
- gene expression
- dna sequences
- motif discovery
- high throughput
- fine grained
- transcription factors
- similarity searching
- drug discovery
- computational methods
- linear support vector machines
- protein function
- drug resistance
- biological processes
- biological data
- sequence alignment
- predicting protein
- statistical significance
- functional modules
- protein complexes
- drug design
- network topology
- high precision
- systems biology
- network analysis
- dna binding
- gene regulation
- regulatory elements
- biomedical literature