Constructing and Analyzing a Large-Scale Gene-to-Gene Regulatory Network-Lasso-Constrained Inference and Biological Validation.
Mikael GustafssonMichael HornquistAnna LombardiPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2005)
Keyphrases
- particle filtering
- gene regulatory networks
- dynamic bayesian networks
- regulatory networks
- systems biology
- gene interactions
- interaction networks
- gene regulation
- biological processes
- particle filter
- biological knowledge
- saccharomyces cerevisiae
- gene function
- gene networks
- bayesian inference
- undirected graphical models
- exact inference
- biological data
- gene expression patterns
- feature selection
- least squares
- protein interaction
- biological networks
- cell cycle
- markov chain monte carlo
- molecular biology
- biological systems
- protein interaction networks
- network model
- signaling pathways
- model selection
- neural network
- bayesian networks
- object oriented
- gene expression data
- prior information
- reverse engineering