Pocketome of Human Kinases: Prioritizing the ATP Binding Sites of (Yet) Untapped Protein Kinases for Drug Discovery.
Andrea VolkamerSameh EidSamo TurkSabrina JaegerFriedrich RippmannSimone FullePublished in: J. Chem. Inf. Model. (2015)
Keyphrases
- virtual screening
- binding sites
- drug discovery
- dna sequences
- protein interaction
- gene expression
- sequence data
- transcription factors
- dna binding
- statistical significance
- biological sequences
- motif discovery
- regulatory elements
- similarity searching
- early stage
- chemical compounds
- microarray
- transcription factor binding sites
- knowledge discovery
- subcellular localization
- biological systems
- computational model
- data mining