An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer.
Raj ChariBradley P. CoeEmily A. VucicWilliam W. LockwoodWan L. LamPublished in: BMC Syst. Biol. (2010)
Keyphrases
- multi dimensional
- gene selection
- gene expression
- differential expression
- biological pathways
- gene expression profiles
- gene interactions
- dna microarray
- metabolic pathways
- gene expression data
- cancer classification
- microarray data
- microarray
- colon cancer
- gene expression datasets
- copy number
- expression profiles
- cancer diagnosis
- complex diseases
- breast cancer
- gene gene interactions
- protein protein interaction networks
- gene gene
- gene expression data sets
- related genes
- tissue samples
- protein interaction data
- genome scale
- experimental conditions
- biologically significant
- genetic regulatory networks
- data sets
- candidate genes
- signaling pathways
- gene networks
- genome wide