Blocking protein-protein interactions: the identification of repetitive turn structures as basis for inhibitor building blocks.
Oliver KochPublished in: J. Cheminformatics (2012)
Keyphrases
- building blocks
- protein protein interactions
- hiv protease
- computational methods
- high throughput
- predicting protein protein interactions
- protein interaction
- biological processes
- gene ontology
- network topology
- biomedical literature
- functional modules
- genomic data
- protein interaction data
- protein function
- systems biology
- biological data
- multiple sequence alignments
- machine learning
- databases
- protein complexes
- mass spectrometry
- biological networks
- database
- computational approaches
- microarray
- text mining
- structural properties
- gene expression data
- high precision
- data processing
- data model
- experimentally determined
- wet lab
- data sets