Identification of Alternative Binding Sites for Inhibitors of HIV-1 Ribonuclease H Through Comparative Analysis of Virtual Enrichment Studies.
Anthony K. FeltsKrystal LaBargeJoseph D. BaumanDishaben V. PatelDaniel HimmelEddy ArnoldMichael A. ParniakRonald M. LevyPublished in: J. Chem. Inf. Model. (2011)
Keyphrases
- comparative analysis
- binding sites
- human immunodeficiency virus
- dna sequences
- genome sequences
- gene expression
- sequence data
- motif discovery
- transcription factors
- statistical significance
- biological sequences
- drug resistance
- dna binding
- co occurrence
- computational models
- pairwise
- drug discovery
- semi quantitative
- similarity measure