Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in eukaryotes.
Michele CaselleFerdinando Di CuntoPaolo ProveroPublished in: BMC Bioinform. (2002)
Keyphrases
- motif discovery
- transcription factors
- gene expression
- binding sites
- microarray
- gene regulation
- regulatory elements
- dna sequences
- dna binding
- gene expression data
- regulatory networks
- biological processes
- transcriptional regulation
- biological networks
- microarray data
- genomic data
- biological sequences
- component analysis
- gene expression patterns
- gene expression profiles
- genome wide
- differentially expressed genes
- highly correlated
- computational biology
- saccharomyces cerevisiae
- co occurrence
- high throughput
- transcription factor binding sites
- gene ontology
- signaling pathways
- natural language processing
- social network analysis
- high dimensionality
- biologically inspired
- sequence data
- molecular biology
- systems biology
- knowledge discovery