Inferring protein fitness landscapes from laboratory evolution experiments.
Sameer D'CostaEmily C. HindsChase R. FreschlinHyebin SongPhilip A. RomeroPublished in: PLoS Comput. Biol. (2023)
Keyphrases
- fitness landscape
- evolution process
- evolutionary process
- natural selection
- evolutionary algorithm
- genetic algorithm
- protein structure
- genetic programming
- protein sequences
- fitness function
- amino acids
- artificial life
- protein structure prediction
- mass spectra
- molecular dynamics
- drug design
- protein folding
- population size
- evolutionary computation
- high precision
- social networks