Allosteric mechanism of the circadian protein Vivid resolved through Markov state model and machine learning analysis.
Hongyu ZhouZheng DongGennady VerkhivkerBrian D. ZoltowskiPeng TaoPublished in: PLoS Comput. Biol. (2019)
Keyphrases
- machine learning
- computational model
- probabilistic model
- empirical data
- formal model
- markov model
- mathematical model
- decision trees
- experimental data
- genetic algorithm
- statistical analysis
- state space
- data mining
- prior knowledge
- pairwise
- high level
- data analysis
- bayesian networks
- conceptual model
- similarity measure
- feature selection
- learning mechanism