Machine Learning Integrating Protein Structure, Sequence, and Dynamics to Predict the Enzyme Activity of Bovine Enterokinase Variants.
Niccolo Alberto Elia VenanziAndrea BasciuAttilio Vittorio VargiuAlexandros KiparissidesPaul A. DalbyDuygu DikiciogluPublished in: J. Chem. Inf. Model. (2024)
Keyphrases
- protein structure
- machine learning
- amino acids
- protein families
- protein sequences
- protein tertiary structure
- protein structural
- predicting protein
- secondary structure
- molecular biology
- tertiary structure
- computational biology
- amino acid sequences
- experimentally determined
- sequence alignment
- psi blast
- sequence analysis
- biological sequences
- protein classification
- protein function
- machine learning methods
- multiple sequence alignments
- protein structure prediction
- feature selection
- protein folding
- data mining
- nuclear magnetic resonance
- natural language processing
- computational approaches
- decision trees
- contact map
- knowledge discovery
- statistical methods
- protein structure alignment
- high accuracy