Cryptic binding site prediction with protein language models.
Vít SkrhakKamila RiedlovaMarian NovotnyDavid HokszaPublished in: BIBM (2023)
Keyphrases
- language model
- protein interaction
- binding sites
- virtual screening
- protein protein
- language modeling
- dna binding
- predicting protein
- document retrieval
- protein protein interactions
- regulatory elements
- drug design
- n gram
- computational methods
- speech recognition
- gene expression
- language modelling
- information retrieval
- query expansion
- test collection
- probabilistic model
- protein function
- dna sequences
- retrieval model
- drug discovery
- protein structure prediction
- prediction accuracy
- transcription factor binding sites
- statistical language models
- vector space model
- protein complexes
- sequence data
- smoothing methods
- statistical significance
- transcription factors
- similarity searching
- biological data
- protein structure
- biological systems
- document ranking
- protein sequences
- biomedical literature
- gene ontology
- cis regulatory
- relevance model