Prediction of the Isoelectric Point of an Amino Acid Based on GA-PLS and SVMs.
Huanxiang LiuRuisheng ZhangXiaojun YaoMancang LiuZhide HuBo Tao FanPublished in: J. Chem. Inf. Model. (2004)
Keyphrases
- amino acids
- protein sequences
- protein structure prediction
- physico chemical
- support vector
- genetic algorithm
- genetic algorithm ga
- tertiary structure
- contact maps
- neural networks and support vector machines
- prediction accuracy
- experimentally determined
- contact map
- secondary structure prediction
- secondary structure
- protein structure
- partial least squares
- support vector machine
- evolutionary algorithm
- amino acid sequences
- prediction model
- kernel function
- machine learning
- protein function
- physicochemical properties
- amino acid residues
- sequence alignment
- psi blast
- computational biology
- latent variables
- kernel methods
- support vector machine svm
- feature space
- protein folding
- fitness function