Differentiation of the Mu-opioid ligand GSK1521498 from naltrexone using [11C]carfentanil PET and fMRI.
John D. BeaverEdward T. BullmoreGraham E. SearleChristopher J. LongSamuel P. HillJonathan HowardPradeep J. NathanPaul M. MatthewsRoger N. GunnEugenii A. RabinerPublished in: NeuroImage (2010)
Keyphrases
- human brain
- functional magnetic resonance imaging
- image reconstruction
- activation detection
- positron emission tomography
- brain imaging
- brain activity
- activation patterns
- drug design
- event related
- pet images
- high throughput
- development environment
- functional mri
- healthy subjects
- magnetic resonance imaging
- image reconstruction algorithms
- brain injury
- cognitive states
- data analysis
- magnetic resonance
- data sets
- drug discovery
- information retrieval