Protein-Protein Interaction Affinity Prediction Based on Interface Descriptors and Machine Learning.
Xueling LiMin ZhuXiao-Lai LiHong-Qiang WangShulin WangPublished in: ICIC (2) (2012)
Keyphrases
- protein protein interactions
- machine learning
- protein interaction
- predicting protein
- drug design
- wet lab
- protein function prediction
- computational methods
- gene ontology
- experimentally determined
- multiple sequence alignments
- network topology
- predicting protein protein interactions
- high throughput
- learning algorithm
- protein protein
- computational approaches
- secondary structure
- structural properties
- data analysis
- protein function
- protein complexes
- functional modules
- biological processes
- supervised learning
- biomedical literature
- databases
- systems biology
- information extraction
- biological networks
- genomic data
- machine learning algorithms
- protein interaction networks
- computational biology
- biological data
- gene expression
- knowledge discovery
- pairwise
- network analysis
- high precision
- social networks
- machine learning methods
- data mining