Ollivier Persistent Ricci Curvature-Based Machine Learning for the Protein-Ligand Binding Affinity Prediction.
Junjie WeeKelin XiaPublished in: J. Chem. Inf. Model. (2021)
Keyphrases
- drug design
- machine learning
- protein secondary structure
- protein structure prediction
- protein secondary structure prediction
- subcellular localization
- recursive neural networks
- contact map
- mhc class ii
- computational biology
- drug discovery
- dna binding
- prediction accuracy
- prediction model
- contact maps
- protein sequences
- protein protein
- learning algorithm
- protein tertiary structure
- protein protein interactions
- virtual screening
- protein classification
- machine learning methods
- machine learning algorithms
- remote homology detection
- pairwise
- predicting protein
- data mining
- transcription factor binding sites
- natural language processing
- protein interaction
- information extraction
- binding sites
- decision trees
- physicochemical properties
- experimentally determined
- affine invariant
- major histocompatibility complex
- amino acids
- feature selection
- high throughput
- secondary structure
- statistical methods