Discovery of lung cancer pathways using Reverse Phase Protein Microarray and prior-knowledge based Bayesian networks.
Dong-Chul KimChin-Rang YangXiaoyu WangBaoju ZhangXiaorong WuJean GaoPublished in: EMBC (2011)
Keyphrases
- microarray
- lung cancer
- protein interaction data
- bayesian networks
- cancer diagnosis
- gene expression data
- signaling pathways
- expression profiles
- high throughput
- gene expression
- regulatory networks
- gene ontology
- systems biology
- early detection
- automated detection
- microarray data
- protein protein interactions
- protein function
- experimental conditions
- gene selection
- cancer classification
- biological processes
- molecular biology
- gene expression profiles
- gene expression analysis
- gene expression profiling
- gene networks
- protein interaction
- differential expression
- biological data
- high dimensionality
- genomic data
- knowledge discovery
- genome wide
- microarray images
- machine learning
- mass spectrometry
- protein protein interaction networks
- cell cycle
- protein structure
- medical images
- protein structure prediction
- data mining
- protein complexes
- functional modules