Identifying biologically interpretable transcription factor knockout targets by jointly analyzing the transcription factor knockout microarray and the ChIP-chip data.
Tzu-Hsien YangWei-Sheng WuPublished in: BMC Syst. Biol. (2012)
Keyphrases
- microarray
- transcription factors
- gene expression
- experimental conditions
- gene expression levels
- high throughput
- regulatory networks
- gene expression data
- binding sites
- data sets
- gene sets
- gene expression datasets
- gene selection
- highly correlated
- differential expression
- genome wide
- dna sequences
- microarray data
- high dimensionality
- microarray datasets
- gene regulation
- component analysis
- biological processes
- gene expression profiles
- expression profiles
- gene ontology
- biological data
- data mining techniques
- high speed
- knowledge discovery
- data points
- saccharomyces cerevisiae
- gene regulatory networks
- gene networks
- cancer classification
- systems biology
- data acquisition
- data sources
- machine learning
- data mining