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Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling.
Stefan Wolfsheimer
Inke Herms
Sven Rahmann
Alexander K. Hartmann
Published in:
BMC Bioinform. (2011)
Keyphrases
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sequence alignment
rare events
importance sampling
pairwise
monte carlo
smith waterman
random sampling
dynamic programming
amino acids
statistical methods
protein sequences
machine learning
multi class
markov chain
class distribution