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Transferable scoring function based on semiempirical quantum mechanical PM6-DH2 method: CDK2 with 15 structurally diverse inhibitors.
Petr Dobes
Jindrich Fanfrlík
Jan Rezác
Michal Otyepka
Pavel Hobza
Published in:
J. Comput. Aided Mol. Des. (2011)
Keyphrases
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scoring function
prior knowledge
similarity measure
probabilistic model
data points
maximum likelihood estimation