RefinePocket: An Attention-Enhanced and Mask-Guided Deep Learning Approach for Protein Binding Site Prediction.
Yongchang LiuPeiying LiShikui TuLei XuPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2023)
Keyphrases
- deep learning
- protein interaction
- binding sites
- virtual screening
- protein protein
- dna binding
- protein protein interactions
- unsupervised learning
- predicting protein
- regulatory elements
- dna sequences
- transcription factor binding sites
- unsupervised feature learning
- protein structure prediction
- machine learning
- computational methods
- drug design
- transcription factors
- protein sequences
- drug discovery
- mental models
- gene expression
- protein interaction networks
- protein function
- statistical significance
- sequence data
- protein complexes
- weakly supervised
- similarity searching
- gene ontology
- high throughput
- biological systems
- systems biology
- computational biology
- amino acids
- protein structure
- pairwise