Fighting Obesity with a Sugar-Based Library: Discovery of Novel MCH-1R Antagonists by a New Computational-VAST Approach for Exploration of GPCR Binding Sites.
Alexander HeifetzOliver BarkerGeraldine VerquinNorbert WimmerWim MeutermansSandeep PalRichard LawMark WhittakerPublished in: J. Chem. Inf. Model. (2013)
Keyphrases
- binding sites
- motif discovery
- dna sequences
- gene expression
- pattern discovery
- biological sequences
- protein families
- protein sequences
- sequence data
- transcription factors
- statistical significance
- dna binding
- protein protein
- data mining tasks
- transcription factor binding sites
- data mining
- regulatory elements
- drosophila melanogaster
- knowledge discovery