Diminished Self-Chaperoning Activity of the ΔF508 Mutant of CFTR Results in Protein Misfolding.
Adrian W. R. SerohijosTamás HegedüsJohn R. RiordanNikolay V. DokholyanPublished in: PLoS Comput. Biol. (2008)
Keyphrases
- amino acids
- protein sequences
- protein structure
- molecular structures
- database
- subcellular localization
- three dimensional
- human activities
- protein protein interaction networks
- activity theory
- protein structure prediction
- sequence alignment
- tandem mass spectra
- protein interaction data
- multiple sequence alignment
- protein folding
- mass spectrometry
- protein protein interactions
- computational methods
- learning algorithm
- data sets