Identification of the key DNA damage response genes for predicting immunotherapy and chemotherapy efficacy in lung adenocarcinoma based on bulk, single-cell RNA sequencing, and spatial transcriptomics.
Shijie SunKai WangDeyu GuoHaotian ZhengYong LiuHongchang ShenJiajun DuPublished in: Comput. Biol. Medicine (2024)
Keyphrases
- high throughput sequencing
- genome wide
- genomic sequences
- genome sequences
- rna sequences
- rna structures
- coding regions
- rna seq
- gene expression
- nucleotide sequences
- human genome
- lung cancer
- sequence data
- dna sequences
- sequenced genomes
- spatial information
- tandem mass spectrometry
- cancer classification
- grid cells
- arabidopsis thaliana
- dna binding
- spatial data
- gene expression profiles
- binding sites
- ct images
- microarray