Genome-wide similarity search for transcription factors and their binding sites in a metal-reducing prokaryote Geobacter sulfurreducens.
Bin YanDerek R. LovleyJulia KrushkalPublished in: Biosyst. (2007)
Keyphrases
- similarity search
- transcription factors
- genome wide
- high throughput
- binding sites
- dna binding
- gene regulation
- human genome
- query processing
- regulatory networks
- similarity measure
- gene expression
- high dimensional
- high dimensional data
- microarray
- knn
- motif discovery
- biological processes
- dna sequences
- regulatory elements
- transcription factor binding sites
- saccharomyces cerevisiae
- machine learning
- component analysis
- signaling pathways
- nearest neighbor
- data processing
- systems biology
- sequence data
- highly correlated