Optimization of in silico tools for predicting genetic variants: individualizing for genes with molecular sub-regional stratification.
Bin TangBin LiLiang-Di GaoNa HeXiao-Rong LiuYue-Sheng LongYang ZengYong-Hong YiTao SuWei-Ping LiaoPublished in: Briefings Bioinform. (2020)
Keyphrases
- gene regulatory networks
- complex diseases
- optimization problems
- optimization algorithm
- genetic algorithm
- cell biology
- interaction networks
- three dimensional
- biological data
- gene expression data
- microarray data
- gene gene interactions
- gene expression
- biological knowledge
- analysis of gene expression data
- experimental conditions
- estimation of distribution algorithms
- protein protein interaction networks
- genetic regulatory networks