PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data.
Daogang GuanJiaofang ShaoZhongying ZhaoPanwen WangJing QinYouping DengKenneth R. BohelerJunwen WangBin YanPublished in: Nucleic Acids Res. (2014)
Keyphrases
- gene expression data
- gene regulatory networks
- biclustering algorithms
- microarray
- gene expression
- saccharomyces cerevisiae
- transcription factors
- biological processes
- systems biology
- regulatory networks
- gene networks
- microarray data
- gene expression patterns
- gene regulation
- data sets
- high dimensionality
- high throughput
- biological networks
- protein protein interactions
- feature selection
- clustering gene expression data
- gene selection
- high dimensional data
- network model
- high dimensional
- gene expression profiles
- protein complexes
- reverse engineering
- protein interaction
- biological data
- functional modules
- protein interaction networks
- microarray datasets
- high precision
- cell cycle
- social networks
- machine learning