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Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations.

Liat Rockah-ShmuelÁgnes Tóth-PetróczyDan S. Tawfik
Published in: PLoS Comput. Biol. (2015)
Keyphrases
  • protein structure
  • search space
  • protein protein interactions
  • parameter space
  • input space
  • protein folding
  • low dimensional
  • vector space
  • amino acids