Targeted profiling of 5-(hydroxy)methylcytosine in genomic DNA from human livers: Next-generation sequencing of target enriched DNA reveals unexpectedly high interindividual variability of cytosine methylation and hydroxymethylation.
Maxim IvanovMagnus Ingelman-SundbergMart KalsLili MilaniPublished in: BIBM (2014)
Keyphrases
- genomic sequences
- dna sequences
- genome sequences
- human genome
- nucleotide sequences
- dna computing
- gene regulation
- high throughput sequencing
- sequence data
- dna sequencing
- biological sequences
- molecular biology
- binding sites
- dna binding
- gene prediction
- coding regions
- evolutionary history
- single nucleotide polymorphisms
- sequence analysis
- genomic data
- motif discovery
- human behavior
- wide range
- genotype phenotype
- data sets
- protein coding regions
- rna seq
- transcription factors
- target object
- protein sequences
- computational models
- human experts
- particle filter
- neural network