Connecting high-dimensional mRNA and miRNA expression data for binary medical classification problems.
Mathias FuchsTim BeißbarthEdgar WingenderKlaus JungPublished in: Comput. Methods Programs Biomed. (2013)
Keyphrases
- regulatory networks
- high dimensional
- genome wide
- microarray data
- gene expression data
- gene expression
- gene function
- expression profiles
- binding sites
- microarray
- gene regulatory networks
- gene sets
- post transcriptional
- gene regulation
- microarray data analysis
- high dimensionality
- high throughput
- gene ontology
- computational methods
- gene expression profiles
- gene networks
- secondary structure
- low dimensional
- high dimensional data
- biological processes
- nearest neighbor
- similarity search
- protein protein interactions
- feature selection
- sequence data
- saccharomyces cerevisiae
- human genome
- microarray datasets
- rna sequences
- dimensionality reduction
- feature space
- data points
- dna sequences
- motif discovery
- gene selection
- transcription factors
- biological systems
- systems biology