Conformational Coupling between Receptor and Kinase Binding Sites through a Conserved Salt Bridge in a Signaling Complex Scaffold Protein.
Davi R. OrtegaGuoya MoKwangwoon LeeHongjun ZhouJérôme BaudryFrederick W. DahlquistIgor B. ZhulinPublished in: PLoS Comput. Biol. (2013)
Keyphrases
- sequence alignment
- binding sites
- influenza virus
- transcription factor binding sites
- dna binding
- protein protein
- gene expression
- sequence data
- dna sequences
- transcription factors
- protein families
- regulatory elements
- protein sequences
- biological sequences
- pairwise
- amino acids
- drosophila melanogaster
- motif discovery
- statistical significance
- coarse grained
- experimentally determined
- protein structure prediction
- protein interaction
- sequence databases
- protein folding
- coding regions
- protein structure
- complex systems
- data analysis