Predicting gene ontology annotations of orphan GWAS genes using protein-protein interactions.
Usha KuppuswamySeshan AnanthasubramanianYanli WangNarayanaswamy BalakrishnanMadhavi GanapathirajuPublished in: Algorithms Mol. Biol. (2014)
Keyphrases
- gene ontology
- protein protein interactions
- interacting proteins
- computational methods
- high throughput
- biological processes
- protein interaction
- biological pathways
- genomic data
- protein function
- biological data
- biomedical literature
- microarray
- high precision
- saccharomyces cerevisiae
- biological networks
- functional modules
- gene sets
- network topology
- cell cycle
- gene networks
- genome wide
- network analysis
- protein interaction networks
- regulatory networks
- biological knowledge
- protein interaction data
- protein function prediction
- databases
- computational approaches
- protein complexes
- structural properties
- genome wide association studies
- information theoretic
- semantic similarity
- machine learning
- data mining
- single nucleotide polymorphisms
- systems biology
- secondary structure
- gene selection