Ligand and structure-based methodologies for the prediction of the activity of G protein-coupled receptor ligands.
Stefano CostanziIrina G. TikhonovaT. Kendall HardenKenneth A. JacobsonPublished in: J. Comput. Aided Mol. Des. (2009)
Keyphrases
- drug design
- drug discovery
- contact map
- protein structure prediction
- virtual screening
- contact maps
- amino acids
- data mining
- early stage
- tertiary structure
- prediction accuracy
- molecular structures
- subcellular localization
- protein sequences
- protein structure
- prediction model
- complex networks
- network structure
- protein protein
- protein function prediction