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The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.

Tiziana SonatiRegina R. ReimannJeppe FalsigPravas Kumar BaralTracy O'ConnorSimone HornemannSine YaganogluBei LiUli S. HerrmannBarbara WielandMridula SwayampakulaMuhammad Hafizur RahmanDipankar DasNat KavRoland RiekPawel P. LiberskiMichael N. G. JamesAdriano Aguzzi
Published in: Nat. (2013)
Keyphrases
  • chemical compounds
  • drug discovery
  • protein structure
  • protein sequences
  • prostate cancer
  • amino acids
  • power law
  • protein folding
  • data sets
  • three dimensional
  • structural features
  • protein function
  • heavy tailed