ADME Properties Evaluation in Drug Discovery: Prediction of Caco-2 Cell Permeability Using a Combination of NSGA-II and Boosting.
Ning-Ning WangJie DongYin-Hua DengMin-Feng ZhuMing WenZhiqiang YaoAiping LuJian-Bing WangDong-Sheng CaoPublished in: J. Chem. Inf. Model. (2016)
Keyphrases
- drug discovery
- nsga ii
- multi objective
- multiobjective optimization
- multi objective optimization
- test problems
- evolutionary algorithm
- subcellular localization
- pareto optimal
- optimization problems
- multiobjective evolutionary algorithm
- evolutionary multiobjective
- optimization algorithm
- evolutionary multiobjective optimization
- virtual screening
- multi objective evolutionary algorithms
- data mining
- optimal solution
- differential evolution
- knapsack problem
- feature selection
- genetic algorithm
- neural network
- scientific data
- databases
- fitness function
- knowledge discovery
- dynamic programming
- data analysis
- objective function
- pharmaceutical industry