ASTER: A Method to Predict Clinically Relevant Synthetic Lethal Genetic Interactions.
Herty LianyAishwarya JayagopalDachuan HuangJing Quan LimNur Izzah NBHAnand JeyasekharanChoon Kiat OngVaibhav RajanPublished in: IEEE J. Biomed. Health Informatics (2024)
Keyphrases
- synthetic data
- high accuracy
- clinically relevant
- fully automatic
- theoretical analysis
- optimization algorithm
- computational cost
- experimental evaluation
- similarity measure
- high precision
- cost function
- pairwise
- preprocessing
- detection method
- clustering method
- support vector machine
- model selection
- mathematical model
- optimization method
- evaluation method
- classification accuracy
- denoising
- data sets
- probabilistic model
- dynamic programming
- significant improvement
- k means
- computational complexity
- bayesian networks
- image segmentation
- feature selection