Detecting gene-gene interactions from GWAS using diffusion kernel principal components.
Andrew WalakiraJunior OciraDiane DurouxRamouna FouladiMiha MoskonDamjana RozmanKristel Van SteenPublished in: BMC Bioinform. (2022)
Keyphrases
- principal components
- kernel space
- genome wide association studies
- gene gene interactions
- principal component analysis
- genome wide
- kernel principal component analysis
- principal component regression
- dimensionality reduction
- complex diseases
- biological data
- feature space
- decision trees
- kernel function
- high throughput
- component analysis
- dimension reduction
- covariance matrix
- human genome
- feature set
- data mining