Improved base-calling and quality scores for 454 sequencing based on a Hurdle Poisson model.
Kristof De BeufJoachim M. De SchrijverOlivier ThasWim Van CriekingeRafael A. IrizarryLieven ClementPublished in: BMC Bioinform. (2012)
Keyphrases
- high quality
- statistical model
- high level
- conceptual model
- experimental data
- probabilistic model
- management system
- probability distribution
- poisson process
- hierarchical model
- simulation model
- computational model
- em algorithm
- neural network
- cost function
- artificial neural networks
- bayesian networks
- case study
- knowledge base