A regression framework incorporating quantitative and negative interaction data improves quantitative prediction of PDZ domain-peptide interaction from primary sequence.
Xiaojian ShaoChris S. H. TanCourtney VossShawn S. C. LiNaiyang DengGary D. BaderPublished in: Bioinform. (2011)
Keyphrases
- input data
- database
- raw data
- data sources
- data sets
- data processing
- prior knowledge
- data collection
- probability distribution
- data points
- knowledge discovery
- semi supervised
- prediction accuracy
- domain experts
- spatial data
- quantitative and qualitative
- data structure
- high quality
- regression model
- training data
- support vector regression
- survival analysis