Fast Protein Binding Site Comparison via an Index-Based Screening Technology.
Mathias M. von BehrenAndrea VolkamerAngela M. HenzlerKaren SchomburgSascha UrbaczekMatthias RareyPublished in: J. Chem. Inf. Model. (2013)
Keyphrases
- virtual screening
- drug discovery
- binding sites
- protein protein
- dna binding
- protein interaction
- sequence alignment
- regulatory elements
- sequence data
- dna sequences
- transcription factor binding sites
- computational methods
- protein protein interactions
- gene expression
- regulatory networks
- index structure
- statistical significance
- protein structure
- protein sequences
- early stage
- motif discovery
- protein families
- high throughput
- machine learning