Development of a novel representation of drug 3D structures and enhancement of the TSR-based method for probing drug and target interactions.
Tarikul I. MilonYuhong WangRyan L. FontenotPoorya KhajouieFrancois VillingerVijay RaghavanWu XuPublished in: Comput. Biol. Chem. (2024)
Keyphrases
- object recognition
- image representation
- cost function
- synthetic data
- significant improvement
- experimental evaluation
- high precision
- preprocessing
- classification accuracy
- generation method
- similarity measure
- clustering method
- detection algorithm
- high accuracy
- probabilistic model
- multiscale
- input data
- support vector machine
- support vector machine svm
- dynamic programming
- detection method
- computational complexity
- objective function