Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection.
Tianwei YuHesen PengPublished in: BMC Bioinform. (2010)
Keyphrases
- model selection
- gaussian mixture model
- mixture model
- statistical inference
- cross validation
- bayesian information criterion
- sample size
- hypothesis tests
- hyperparameters
- density estimation
- bayesian learning
- machine learning
- selection criterion
- feature vectors
- maximum likelihood criterion
- parameter estimation
- em algorithm
- expectation maximization
- regression model
- multivariate regression
- model selection criteria
- variable selection
- maximum likelihood
- least squares
- markov random field
- gaussian distribution
- gaussian process
- statistical methods
- probability density function
- automatic model selection
- information criterion
- marginal likelihood
- feature extraction
- denoising
- data mining
- information retrieval
- feature space
- prior knowledge